| Molecular Formula | C11H14O3 |
| Molar Mass | 194.23 |
| Density | 1.170±0.06 g/cm3(Predicted) |
| Boling Point | 342.8±17.0 °C(Predicted) |
| pKa | 4.47±0.10(Predicted) |
| Physical and Chemical Properties | Chemical Properties This product is a white needle crystal, m.p.171 ~ 173 ℃, slightly soluble in water, soluble in hot water, soluble in organic solvents such as alcohol and benzene. |
| Use | Use 2-(4-hydroxyphenyl)-3-methylbutyric acid is an intermediate of flufenvalerate and deltamethrin. |
| Raw Materials | Fenvalerate ALPHA-ISOPROPYL-4-CHLOROPHENYLACETIC ACID 3-Methylbutanenitrile |
| Downstream Products | 2-(4-difluoromethoxy)phenyl-3-methyl butyric acid |
Japan's Ihara Chemical Company once proposed that 2-(4-chlorophenyl)-3-methylbutyronitrile be hydrolyzed under pressure. Zhang Zheng et al. proposed that 2-(4-chlorophenyl)-3-methylbutyric acid should be reacted in the presence of catalysts Cu and Cu2O at a temperature of 180 ℃. The reaction should be carried out under normal pressure with a yield of ≥ 90% and the catalyst can be reused. The method is simple, industrialized, and can use the intermediate 2-(4-chlorophenyl)-3-methylbutyric acid for the production of fenvalerate as a raw material.
Place 2-(4-chlorophenyl)-3-methylbutyric acid, water, sodium hydroxide and complex copper catalyst in an elastic autoclave, heat to 180 ℃, react for 5h, add 4 times the amount of water of butyric acid after cooling, filter, recover the copper catalyst, adjust the pH = 2-3 with concentrated hydrochloric acid to obtain a gray solid, recrystallize to obtain white needle-like crystals, m.p.171.